Biomarkers of Healthy and Diseased Pulp and Periapical Tissue: A Review

Abstract

Establishing an accurate diagnosis is the first and prime requisite, in initiating the correct treatment, but unfortunately due to the limitations of the diagnostic procedure, this step can be highly confounding. Biological marker serves as a parameter, that is indicative of underlying physiology and health of the tissue. Healthy and diseased pulp and periapical tissue, tend to reflect physiologic and pathologic agents, which on isolation and estimation, can help diagnose, the condition more conclusively. Use of these agents, along with signs, symptoms, result of various tests, can aid in establishing the condition, more precisely. This review article focuses upon, identification of biomarkers, that play important role in pathogenesis of dental caries, pulpal and periapical pathosis and help to diagnose the pathological and healthy condition accurately, thus guide decisions, regarding clinical treatment.

Key words: biological products, biomarkers, dental Caries, dental Pulp, diagnostic Tests