The Management of Gingival/Mucosal Fenestration Defect Using Nanocrystalline Hydroxyapatite Bone Substitute with L-PRF : A Case Report
Keywords:
Mucosal fenestration, endodontic treatment, leukocyte and platelet-rich fibrin, Bone graft, Connective tissue graft
Abstract
Clinically, mucosal fenestrations are uncommon and often challenging to treat. Most of the time, there are aesthetic considerations. The case report of a 24-year-old female patient with a history of childhood trauma is highlighted in this article. She presented with aesthetic concerns regarding gingival/mucosal fenestration in her right lower central incisor. In this instance, a conservative endodontic and regenerative therapy approach using synthetic nanocrystaline hydroxyapatite bone substitute with leukocyte and platelet-rich fibrin was used to treat mucosal fenestration. A complete mucosal fenestration coverage with satisfactory aesthetic result outcome was achieved/obtained.
References
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9. Rupprecht RD, Horning GM, Nicoll BK, Cohen ME. Prevalence of dehiscences and fenestrations in modern American skulls. J Periodontol. 2001;72(6):722–9. doi: 10.1902/jop.2001.72.6.722.
10. Jafri Z, Sultan N, Ahmad N, Daing A. An infrequent clinical case of mucosal fenestration:Treated with an interdisciplinary approach and regenerative therapy. J Indian Soc Periodontol. 2019;23(2):168–71.
11. Travassos R, Soares B, Bhandi SH, Silva MB, Bandéca MC, Mouchrek JC, Jr, et al. Multidisciplinary treatment of a fenestration-type defect. J Contemp Dent Pract. 2015;16(4):329–34.
12. Asti A., Gioglio L. Natural and synthetic biodegradable polymers: Different scaffolds for cell expansion and tissue formation. Int. J. Artif. Organs. 2014;37:187–205.
13. Toffler M, Toscano N, Holtzclaw D, Corso M, Dohan D. Introducing Choukroun’s platelet rich fibrin (PRF) to the reconstructive surgery milieu. J Implant Adv Clin Dent. 2009;1:22–31.
14. Kobayashi E, Fluckiger L, Fujioka-Kobayashi M, Sawada K, Sculean A, Schaller B, et al. Comparative release of growth factors from PRP, PRF, and advanced-PRF. Clinical oral investigations. 2016.
2. 2. Serrano J. Gingivo-osseous pathologic fenestration. Oral Surg Oral Med Oral Pathol 1971;32:697-700.
3. Treatment of a labial fenestration of a lower incisor tooth apex. Rawlinson A. Br Dent J. 1984;156:448–449. doi: 10.1038/sj.bdj.4805397.
4. Tseng CC, Chen YH, Huang CC, Bowers GM. Correction of a large periradicular lesion and mucosal defect using combined endodontic and periodontal therapy: a case report. Int J Periodontics Restorative Dent. 1995;15:377-383.
5. Lin YC, Lee YY, Ho YC, Hsieh YC, Lai YL, Lee SY. Treatment of large apical lesions with mucosal fenestration: a clinical study with longterm evaluation. J Endod. 2015;41:563-567.
6. Ju YR, Tsai AH, Wu YJ, Pan WL. Surgical intervention of mucosal fenestration in a maxillary premolar: a case report. Quintessence Int. 2004;35:125-128.
7. Ricucci D, Siqueira JF, Loghin S, et al. Management and Histobacteriological findings of mucosal fenestration: a report of 2 cases. J Endod. 2018;44:1583-1592.
8. Miron RJ, Zucchelli G, Pikos MA, et al. Use of platelet-rich fibrin in regenerative dentistry: a systematic review. Clin Oral Investig. 2017; 21:1913-1927
9. Rupprecht RD, Horning GM, Nicoll BK, Cohen ME. Prevalence of dehiscences and fenestrations in modern American skulls. J Periodontol. 2001;72(6):722–9. doi: 10.1902/jop.2001.72.6.722.
10. Jafri Z, Sultan N, Ahmad N, Daing A. An infrequent clinical case of mucosal fenestration:Treated with an interdisciplinary approach and regenerative therapy. J Indian Soc Periodontol. 2019;23(2):168–71.
11. Travassos R, Soares B, Bhandi SH, Silva MB, Bandéca MC, Mouchrek JC, Jr, et al. Multidisciplinary treatment of a fenestration-type defect. J Contemp Dent Pract. 2015;16(4):329–34.
12. Asti A., Gioglio L. Natural and synthetic biodegradable polymers: Different scaffolds for cell expansion and tissue formation. Int. J. Artif. Organs. 2014;37:187–205.
13. Toffler M, Toscano N, Holtzclaw D, Corso M, Dohan D. Introducing Choukroun’s platelet rich fibrin (PRF) to the reconstructive surgery milieu. J Implant Adv Clin Dent. 2009;1:22–31.
14. Kobayashi E, Fluckiger L, Fujioka-Kobayashi M, Sawada K, Sculean A, Schaller B, et al. Comparative release of growth factors from PRP, PRF, and advanced-PRF. Clinical oral investigations. 2016.
Published
2025-04-24
How to Cite
Soni, D. P., Kapoor, D. A., Saini, D. N., & Dr. Shri Ram Soni. (2025). The Management of Gingival/Mucosal Fenestration Defect Using Nanocrystalline Hydroxyapatite Bone Substitute with L-PRF : A Case Report. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 11(2). https://doi.org/10.21276/ujds.2025.v11.i2.8
Section
Case Reports
