The Spectrum of Disorder : Cleidocranial Dysplasia

Keywords: Keywords : Cleidocranial dysplasia, CBFA1, RUNX2


Cleidocranial dysplasia (CCD) is a complex congenital defect characterized by dysplastic bone formation. It is caused by mutations in 6p21 gene encoding transcription factor Core Binding Factor Subunit Alpha 1 ( CBFA1) or Runt related transcription factor 2 (RUNX2) , which is involved in osteoblasts differentiation and bone formation. This paper reports a case of 20 year old female patient with cleidocranial dysplasia and the characteristic routine radiographs aided diagnostic conclusion to the case.



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How to Cite
Khanal , N. (2023). The Spectrum of Disorder : Cleidocranial Dysplasia. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 10(1).